Characteristics and mortality rate of neonates with congenital cytomegalovirus infection
نویسندگان
چکیده
منابع مشابه
Rapid diagnosis of cytomegalovirus infection in congenital neonates.
Immunostaining was compared with PCR for diagnosis of congenital CMV infection. IgM and IgG antibody assays were also performed in parallel. Immunostaining gave sensitivity and specificity of 60% and 97% respectively. Correlations among immunostaining, PCR and the presence of IgM antibody was reported. Immunostaining can be used for early diagnosis of congenital CMV infection in parallel with d...
متن کاملDiagnosis of Congenital Cytomegalovirus Infection in High Risk Neonates
OBJECTIVES This study aimed to compare polymerase chain reaction (PCR) and IgM detection using enzyme linked immune-sorbent assay (ELISA) in diagnosis of congenital cytomegalovirus (CMV) infection. METHODS This study was conducted from May 2009 to December 2010. Urine and blood samples were collected from 94 neonates with suspected congenital CMV infection. Serum and part of urine samples wer...
متن کاملCongenital cytomegalovirus virus infection.
A 14 months old male child with psychomotor retardation and hypotonia is reported, where computerized axial tomography revealed multiple calcification and ventriculomegaly secondary to cortical atrophy. Investigation suggested the diagnosis of cytomegalovirus infection. Importance of early diagnosis is emphasized as the potential long term sequelae can be prevented or reduced markedly with avai...
متن کامل[Congenital cytomegalovirus infection].
Cytomegalovirus (CMV) belongs to the herpesvirus family. Its distribution is ubiquitous in man and many other mammals. CMV causes a typical cytopathic effect with enlargement of the cells that contain intranuclear and cytoplasmic inclusions. CMV is spread directly or by a contact with secretions. Nosocomial transmission can occur during blood transfusion or organ transplantation. Virus excretio...
متن کاملCongenital and perinatal cytomegalovirus infection
Cytomegalovirus (CMV) is currently the most common agent of congenital infection and the leading infectious cause of brain damage and hearing loss in children. Symptomatic congenital CMV infections usually result from maternal primary infection during early pregnancy. One half of symptomatic infants have cytomegalic inclusion disease (CID), which is characterized by involvement of multiple orga...
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ژورنال
عنوان ژورنال: South African Journal of Child Health
سال: 2014
ISSN: 1999-7671,1994-3032
DOI: 10.7196/sajch.752